Induction of classical transplantation tolerance in the adult.
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چکیده
منابع مشابه
Induction of classical transplantation tolerance in the adult
Transplantation tolerance across histoincompatibilities in multiple non-H-2 minors (B10.BR into CBA/Ca) and "minor" plus H-2D (B10.A into CBA/Ca) antigens has been achieved successfully by combined adult bone marrow transplantation and treatment with CD4 and CD8 mAbs. The tolerant state was confirmed by permanent acceptance of donor strain skin grafts, and in vitro unresponsiveness to donor cel...
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Clinical organ transplantation between genetically disparate individuals presently requires nonspecific immunosuppressive agents to prevent rejection . However, the use of such agents risks morbidity and mortality from a range of associated side effects and does not always guarantee success of the graft. Therefore, there is a need to establish methods of "donor-specific transplantation toleranc...
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ژورنال
عنوان ژورنال: Journal of Experimental Medicine
سال: 1989
ISSN: 0022-1007,1540-9538
DOI: 10.1084/jem.169.3.779